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What is Heart Failure with Preserved Ejection Fraction (HFpEF)? Heart failure is a situation during which the heart muscle is unable to pump enough blood to satisfy the body’s nutrition and oxygen wants. We classify heart failure based on which of these two features is abnormal. If the heart muscle is just too weak, the condition is known as heart failure with a decreased ejection fraction (HFrEF). Ejection fraction is used to assess the pump operate of the guts
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